ACCELERATED PARTIAL BREAST IRRADIATION (APBI)

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Accelerated Partial-breast Irradiation (APBI) is a treatment alternative for women with breast cancer. It works by delivering radiation from inside the lumpectomy cavity and is delivered on an outpatient basis twice a day usually for 5 days.

The SAVI™ Brachytherapy System delivers HDR brachytherapy through a multi-catheter applicator that enables more precise delivery of radiation than other breast brachytherapy methods. It allows us to customize radiation treatments based on patient-specific anatomy.

SAVI’s open architecture precisely targets radiation where it is needed most, resulting in better outcomes for patients – including reduced radiation exposure to critical structures such as the ribs, lungs and heart, as well as less skin toxicity, lower persistent seroma rates, and a reduced risk of infection.

Unlike other brachytherapy techniques, SAVI has no skin spacing restrictions, which allows treatment for a wider array of body types. Clinical studies show that nearly twice as many women can be safely treated with SAVI due to its ability to sculpt the dose away from the skin and chest wall without sacrificing overall treatment coverage.

After the surgeon performs the lumpectomy, a collapsed multi-catheter applicator is placed inside the cavity while a portion of the applicator remains outside of the breast. Once in place, the bundle of catheters is slowly expanded to an oval shape so that the radiation dose conforms to the size and shape of the area to be treated.

During the radiation treatment session, the individual catheters are connected to an HDR afterloader for delivery of the radiation source. By having multiple catheters, it offers greater flexibility to contour the dose in a similar manner as interstitial brachytherapy. This gives us the ability to treat more women with varying breast sizes. Once the treatment is complete, the machine is disconnected from the SAVI catheter. Usually on the same day as the final radiation treatment, the SAVI applicator is collapsed and easily removed. No radiation will remain in the breast between treatments or after the final treatment.

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